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Patients with a history of pancreatitis should be evaluated carefully before initiating treatment with Semaglutide / Cyanocobalamin Injection, as GLP-1 receptor agonists have been associated with acute pancreatitis in post-marketing surveillance, though a definitive causal relationship has not been established
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Similarly, treatment of GLP-1RAs induced proliferation and neogenesis of pancreatic -cell in animal models [59]
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